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BIOTEC: Single-Molecule, Real-Time (SMRT™) DNA

We use single-molecule high-resolution dual-trap optical tweezers to characterize molecule-scale force generation and movement by RNA polymerases. We study the molecular events that are at the heart of transcription, and how they give rise to more general types of behaviors such as transcriptional pausing and proofreading.

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Institute for Integrative Nanosciences (IIN) - IFW Dresden

Nucleosomal arrangement affects single-molecule transcription dynamics Veronika Fitza,b, Jaeoh Shinc, Christoph Ehrlicha,b, Lucas Farnungd, Patrick Cramerd, Vasily Zaburdaevc, and Stephan W. Grilla,b,c,1 aBiotechnology Center, Technical University Dresden, 01307 Dresden, Germany; bMax Planck Institute of Molecular Cell Biology and Genetics, 01307

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Kröger Group - Home | B CUBE Center for Molecular

Sequencers & Genome Mapping Sequel (Pacific Bioscience of California, Inc.) The Single Molecule Realtime Sequencing technology (SMRT) from Pacific Biosciences provides sequencing of very long fragments at moderate throughput, particularly interesting …

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single molecule Molecular Inversion Probes (smMIPs

Single Molecule Machines Group Dr. Francesca Moresco. Photo: Jürgen Lösel Group Leader: Dr. Francesca Moresco. The Single Molecule Machines group uses atomic and molecular manipulation as well as on-surface synthesis methods to exploit the quantum mechanical properties of molecular and atomic structures for applications in electronics and mechanics at the nanoscale.

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PacBio SEQUEL SMRT long read sequencing system

single molecule Molecular Inversion Probes (smMIPs) smMIPs is a very cost-effective capture method of the genomic regions of interest and reprensets a modification of the molecular inversion probes (MIP) technology resulting in a highly sensitive variant calling and precise quantitation of mutation frequency, therefore addressing not only germline but also postzygotic somatic mutations [3].

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Diez Group - Home | B CUBE Center for Molecular Bioengineering

Sie suchen nach einer neuen beruflichen Herausforderung? Wir können Ihnen helfen. Sehen Sie sich 295 DRESDEN, SACHSEN PERSONALWESEN Stellenangebote von Unternehmen an, die derzeit neue Mitarbeiter suchen. Mithilfe von Gigajob finden Sie schnell neue Stellen zu personalwesen in Dresden, Sachsen und können sich direkt bewerben. Außerdem haben Sie die Möglichkeit, Gehälter zu …

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Zlotnikov Group - Home | B CUBE Center for Molecular

Yet motivation, justification and implementation vary considerably depending on the problem. The focus of this year’s Atomic Physics workshop will provide a synopsis and at the same time a possibility for cross fertilization of trajectory approaches in atomic, molecular, optical and plasma physics.

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Home - cfaed - TU Dresden

DRESDEN offers a wide spectrum of BIOPHYSICS. Biophysical research in Dresden offers a tremendous width in both, research topics and methods. As such, the dynamics of single molecules, the mechanics of single cells as well as the organisation of tissues are likewise addressed by experimental and theoretical approaches.

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Single-Molecule Micromanipulation Techniques - TU Dresden

At Pacific Biosciences, we are developing applications to observe individual biomolecules at work in real time in nanostructures. The first is monitoring DNA synthesis by single DNA polymerase molecules, allowing the speed, processivity, and efficiency of the enzyme …

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Zhang Group - Home | B CUBE Center for Molecular

We are excited to invite you to the Max Bergmann Symposium 2020 in Dresden, Germany. The symposium will take place at the Steigenberger Hotel in the historic city center. The meeting will include talks by leading scientists from around the world. The event aims to offer a cross-disciplinary perspective on molecular self-assembly and self

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Current-induced conformational switching in single

Experiments, considered till recently unthinkable, are now routine for many laboratories. It is possible, e.g., to measure the electric current flowing through an atomic contact, a single small aromatic molecule or even through a short DNA oligomer.

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BIOPHYSIKdresden

Mikhail V. Tsurkan Leibniz Institute of Polymer Research Dresden, Center for Regenerative Therapies Dresden Verified email at ipfdd.de. Simultaneous single-molecule force and fluorescence sampling of DNA nanostructure conformations using magnetic tweezers. FE Kemmerich, M Swoboda, DJ Kauert, MS Grieb, S Hahn,

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Casual Dating Kostenlos - Such Casual Dating Kostenlos

The research of the Kröger group focuses on diatoms, which are a large group of eukaryotic microalgae. We apply biochemical, molecular genetic, and cell biological methods to investigate two remarkable biological phenomena exhibited by diatoms: silica biomineralization and underwater adhesion.

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Michael Schlierf - Google Scholar Citations

Located in Dresden, Germany, DKMS Life Science Lab is one of the world's largest and most advanced genotyping service providers. Our main focus is high resolution, …

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Nanocar Race II: Pre-registration is Open — TU Dresden

Influence of molecular architecture on the phase behavior in thin films of cylinder forming block copolymers — • L. A. Tsarkova, A. Knoll, and R. Magerle 12:00 CPP 22.45

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TUD, chair Cuniberti "materials science and nanotechnology

[Deutsche Version unter "read more"] The European FET OPEN project MEMO (Mechanics with Molecules) is organizing the 2nd international Nanocar Race (Nanocar Race II), which will take place in 2021 at the CEMES-CNRS in Toulouse, France. The pre-registration for Nanocar Race II is now open and will close at the end of June 2018.

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Advanced Imaging - Services | BioTechnology Platform

Current-induced conformational switching in single-molecule junctions than a full vibration period. Thus, the molecule returns to its original conformation with high probability, and confor-mational switching occurs rarely. Such low-quantum-yield switching has been observed in recent experiments [16, 27, 28].

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Benedikt Sohmen — SingleMolecule

This tutorial will describe on how to track molecules or particles in FIESTA: FIESTA determines the type of object to be tracked via the area threshold specified in the configuration dialog.If you only want to track single molecules or particles you can tell FIESTA only to look for 'molecules' by checking the molecule check-box in the general options of the configuration dialog.

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Max Bergmann Symposium | Dresden | May 2020

05.03.2018 · The European FET OPEN project MEMO (Mechanics with Molecules), started in October 2017, has the goal to construct and test single molecule machines on a surface one at a time, controlling the rotation and the work delivered by a single molecule-motor directly at the atomic scale.

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Nanocar Race II Pre-registration is Open - cfaed | TU Dresden

Title: In situ single-molecule imaging of the bacterial DNA damage response Abstract: Emergence of antibiotic resistance among pathogenic bacteria remains a major challenge in modern medicine. As novel targets for antibiotic development become scarce, recent efforts have focused on understanding and preventing the rapid evolution towards

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Nanomechanics Lab | Dresden Technology Portal

Im Exzellenz-Zentrum für fortgeschrittene Elektronik (cfaed) der TU Dresden arbeitet ihre Gruppe für „Single Molecule Machines“ an der Idee, die Grenzen heutiger Mikroelektronik auf dem mechanischen Pfad zu überschreiten: Die Wissenschaftler wollen Rechenwerke aus Zahnrädern und Motoren konstruieren, von denen die meisten Bauteile nur

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TUD, chair Cuniberti "materials science and nanotechnology

Zhang Y, Erdmann F, Fischer G Nature Chem. Biol. 2009 5(10):724-6. High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical libraries. Mannocci L, Zhang Y, Scheuermann J, Leimbacher M, De Bellis G, Rizzi E, Dumelin C, Melkko S, Neri D. Proc. Natl. Acad. Sci. 2008 105(46):17670.

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SMMs - IFW Dresden

TU Dresden Nanobiophysics, M.Sc. Single Molecule Biophysics, Cytoskeleton 10/2010 - 09/2013 TU Bergakademie Freiberg Angewandte Naturwissenschaft, B.Sc. Festkörperphysik Roman Renger spricht folgende Sprachen: Deutsch (Muttersprache) Englisch

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MPI-CBG: Long read DNA sequencing

The molecules retaining their magnetization in the absence of magnetic field are known as single molecule magnets (SMMs). Important problems to be solved on the way to the applications of SMMs in molecular spintronics is their deposition on surfaces and addressing their spins on the single molecular …

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Startseite - Technische Universität Dresden — TU

This joint database provides scientific instruments, services and technologies offered by research institutions in Dresden.

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Excitons in molecular crystals: Interference between

How does a cell work, mechanically? How do the individual components, molecules and proteins work to fulfill their cellular function? Our long term goal is by applying and developing state-of-the-art single molecule techniques to learn more about the mechanical aspects of protein-protein interactions.

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www.ifw-dresden.de

The students gain a broad overview of molecular and cellular biophysics and molecular nanostructures and machines in theory and experiments. To stress the molecular approach, the programme also covers modern single molecule techniques (single molecule optics, scanning probe techniques) that are fundamental in both biophysics and nanophysics.

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DKMS Life Science Lab

We are one of three platforms of the Dresden Genome Center (a cooperation between the TU Dresden and MPI-CBG), and as such we are applying different long read sequencing, haplotyping, and scaffolding technologies to improve de novo whole genome assemblies. We are also offering additional long read applications, for example sequencing of long RNA isoforms and barcoded amplicon sequencing.

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Schlierf Group - Home | B CUBE Center for Molecular

The Institute for Integrative Nanosciences IIN was founded on 1 st March 2007. About 70-80 scientists and staff members originating from more than ten different nations carry out research both at our main location in Dresden but also at our research site in Chemnitz which was founded two years later in 2009.

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Advanced Imaging - Equipment | BioTechnology Platform

www.ifw-dresden.de

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ERC GraM3 - IFW Dresden

Living organisms form complex mineralized biocomposites that perform a variety of essential functions.These biomaterials are often multifunctional, being responsible for not only structural support and mechanical strength, but also provide optical, magnetic or sensing capabilities.

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BIOTEC: In situ single-molecule imaging of the bacterial

Single-molecule techniques like single-particle tracking (SPT) and Förster resonance energy transfer (FRET) are offered along with the necessary analysis tools. The Interferometric Scattering Microscopy (iSCAT) technique is especially interesting for label-free detection of biomolecules or high-speed single-molecule tracking.